People spend most of their time indoors, whether at home, work, school, or in different public spaces. This prolonged indoor exposure creates an environment where respiratory viruses can easily spread, especially when ventilation is inadequate. Yet, we often overlook the quality of the air we breathe indoors. This oversight has significant consequences; airborne viruses can circulate and linger in poorly ventilated spaces, substantially increasing the risk of infections. The COVID-19 pandemic served as a stark reminder that the air we breathe is not just a passive background to our lives but an active component of our health.

Research has shown that proper ventilation can significantly reduce the risk of airborne infection. By introducing fresh outside air and removing contaminated indoor air, we can decrease the concentration of viral particles in our living and working environments. But the key questions remain: How can we effectively improve indoor air quality? And what science-based strategies can help mitigate airborne infection transmission?

A science-based approach to airborne infection control

The MIST project, funded by the Dutch Research Council (NWO), responds to this crucial need. This project unites a multidisciplinary team of experts in virology, epidemiology, fluid dynamics, molecular biology, medicine, and engineering. Together, they are dedicated to developing evidence-based strategies to mitigate airborne infections. With the collaboration of 28 industry partners, MIST bridges the gap between scientific research and practical applications. The research goes beyond theory, focusing on practical solutions that can be implemented in real-world settings to ensure clean indoor air in shared spaces.

Key objectives of the MIST project:

• Understanding the airborne transmission dynamics of various viruses
• Advancing fundamental research on effective ventilation systems, air purification, and personal protection measures, including proximity and mask usage
• Developing evidence-based guidelines for infection prevention in shared spaces such as offices, schools, and healthcare centres

By combining expertise across multiple disciplines and working closely with industry partners, the MIST project ensures that its findings lead to effective, science-based solutions for ventilation, air cleaning, and personal protection measures to prevent infections. As we continue to navigate the post-pandemic world, the MIST project remains committed to enhancing public health by creating healthier and cleaner indoor air in shared spaces.

For more information about our research, partners, and funders, visit our website: www.mist-project.nl